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Membrane bending and sphingomyelinase-associated, sulfatide-dependent hypoxic adhesion of sickle mature erythrocytes
Abnormal erythrocyte adhesion owing to polymerization of sickle hemoglobin is central to the pathophysiology of sickle cell disease (SCD). Mature erythrocytes constitute >80% of all erythrocytes in SCD; however, the relative contributions of erythrocytes to acute and chronic vasculopathy in SCD a...
Autores principales: | Goreke, Utku, Kucukal, Erdem, Wang, Fang, An, Ran, Arnold, Nicole, Quinn, Erina, Yuan, Charlotte, Bode, Allison, Hill, Ailis, Man, Yuncheng, Hambley, Bryan C., Schilz, Robert, Ginwalla, Mahazarin, Little, Jane A., Gurkan, Umut A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society of Hematology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196783/ https://www.ncbi.nlm.nih.gov/pubmed/36652689 http://dx.doi.org/10.1182/bloodadvances.2022008392 |
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