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Genome-wide contributions of the MutSα- and MutSβ-dependent DNA mismatch repair pathways to the maintenance of genetic stability in Saccharomyces cerevisiae

The DNA mismatch repair (MMR) system is a major DNA repair system that suppresses both inherited and sporadic cancers in humans. In eukaryotes, the MutSα-dependent and MutSβ-dependent MMR pathways correct DNA polymerase errors. Here, we investigated these two pathways on a whole genome level in Sacc...

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Detalles Bibliográficos
Autores principales: Kadyrova, Lyudmila Y., Mieczkowski, Piotr A., Kadyrov, Farid A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196800/
https://www.ncbi.nlm.nih.gov/pubmed/37059180
http://dx.doi.org/10.1016/j.jbc.2023.104705