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Oxygen modulates iron homeostasis by switching iron sensing of NCOA4

To ensure proper utilization of iron and avoid its toxicity, cells are equipped with iron-sensing proteins to maintain cellular iron homeostasis. We showed previously that nuclear receptor coactivator 4 (NCOA4), a ferritin-specific autophagy adapter, intricately regulates the fate of ferritin; upon...

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Detalles Bibliográficos
Autores principales: Kuno, Sota, Iwai, Kazuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196804/
https://www.ncbi.nlm.nih.gov/pubmed/37059186
http://dx.doi.org/10.1016/j.jbc.2023.104701