Drug screening in zebrafish larvae reveals inflammation-related modulators of secondary damage after spinal cord injury in mice

Prolonged inflammation after spinal cord injury is detrimental to recovery. To find pharmacological modulators of the inflammation response, we designed a rapid drug screening paradigm in larval zebrafish followed by testing of hit compounds in a mouse spinal cord injury model. Methods: We used redu...

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Detalles Bibliográficos
Autores principales: Oprişoreanu, Ana-Maria, Ryan, Fari, Richmond, Claire, Dzekhtsiarova, Yuliya, Carragher, Neil O., Becker, Thomas, David, Samuel, Becker, Catherina G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196818/
https://www.ncbi.nlm.nih.gov/pubmed/37215570
http://dx.doi.org/10.7150/thno.81332

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196818/
https://www.ncbi.nlm.nih.gov/pubmed/37215570
http://dx.doi.org/10.7150/thno.81332

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