Human iPSC-derived midbrain organoids functionally integrate into striatum circuits and restore motor function in a mouse model of Parkinson's disease

Rationale: Parkinson's disease (PD) is a prevalent neurodegenerative disorder that is characterized by degeneration of dopaminergic neurons (DA) at the substantia nigra pas compacta (SNpc). Cell therapy has been proposed as a potential treatment option for PD, with the aim of replenishing the l...

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Detalles Bibliográficos
Autores principales: Zheng, Xin, Han, Deqiang, Liu, Weihua, Wang, Xueyao, Pan, Na, Wang, Yuping, Chen, Zhiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196819/
https://www.ncbi.nlm.nih.gov/pubmed/37215566
http://dx.doi.org/10.7150/thno.80271

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196819/
https://www.ncbi.nlm.nih.gov/pubmed/37215566
http://dx.doi.org/10.7150/thno.80271

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