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Non-canonical integrin signaling activates EGFR and RAS-MAPK-ERK signaling in small cell lung cancer

Background: Small cell lung cancer (SCLC) is an extremely aggressive cancer type with a patient median survival of 6-12 months. Epidermal growth factor (EGF) signaling plays an important role in triggering SCLC. In addition, growth factor-dependent signals and alpha-, beta-integrin (ITGA, ITGB) hete...

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Detalles Bibliográficos
Autores principales: Rubio, Karla, Romero-Olmedo, Addi J., Sarvari, Pouya, Swaminathan, Guruprasadh, Ranvir, Vikas P., Rogel-Ayala, Diana G., Cordero, Julio, Günther, Stefan, Mehta, Aditi, Bassaly, Birgit, Braubach, Peter, Wygrecka, Malgorzata, Gattenlöhner, Stefan, Tresch, Achim, Braun, Thomas, Dobreva, Gergana, Rivera, Miguel N., Singh, Indrabahadur, Graumann, Johannes, Barreto, Guillermo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196829/
https://www.ncbi.nlm.nih.gov/pubmed/37215577
http://dx.doi.org/10.7150/thno.79493