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In vivo imaging of CD8(+) T cells in metastatic cancer patients: first clinical experience with simultaneous [(89)Zr]Zr-Df-IAB22M2C PET/MRI

Aim/Introduction: Despite the spectacular success of immune checkpoint inhibitor therapy (ICT) in patients with metastatic cancer, only a limited proportion of patients benefit from ICT. CD8(+) cytotoxic T cells are important gatekeepers for the therapeutic response to ICT and are able to recognize...

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Detalles Bibliográficos
Autores principales: Schwenck, Johannes, Sonanini, Dominik, Seyfried, Dominik, Ehrlichmann, Walter, Kienzle, Gabriele, Reischl, Gerald, Krezer, Pascal, Wilson, Ian, Korn, Ron, Gonzalez-Menendez, Irene, Quintanilla-Martinez, Leticia, Seith, Ferdinand, Forschner, Andrea, Eigentler, Thomas, Zender, Lars, Röcken, Martin, Pichler, Bernd J, Flatz, Lukas, Kneilling, Manfred, la Fougere, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196830/
https://www.ncbi.nlm.nih.gov/pubmed/37215571
http://dx.doi.org/10.7150/thno.79976