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Dephosphorylation of neural wiring protein shootin1 by PP1 phosphatase regulates netrin-1-induced axon guidance

Axon pathfinding is an essential step in neuronal network formation. Shootin1a is a clutch-linker molecule that is mechanically involved in axon outgrowth and guidance. It was previously shown that concentration gradients of axon guidance molecule netrin-1 in the extracellular environment elicit asy...

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Detalles Bibliográficos
Autores principales: Kastian, Ria Fajarwati, Baba, Kentarou, Kaewkascholkul, Napol, Sasaki, Hisashi, Watanabe, Rikiya, Toriyama, Michinori, Inagaki, Naoyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196999/
https://www.ncbi.nlm.nih.gov/pubmed/37044214
http://dx.doi.org/10.1016/j.jbc.2023.104687