Mass Spectrometry of RNA-Binding Proteins during Liquid–Liquid Phase Separation Reveals Distinct Assembly Mechanisms and Droplet Architectures

[Image: see text] Liquid–liquid phase separation (LLPS) of heterogeneous ribonucleoproteins (hnRNPs) drives the formation of membraneless organelles, but structural information about their assembled states is still lacking. Here, we address this challenge through a combination of protein engineering...

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Detalles Bibliográficos
Autores principales: Sahin, Cagla, Motso, Aikaterini, Gu, Xinyu, Feyrer, Hannes, Lama, Dilraj, Arndt, Tina, Rising, Anna, Gese, Genis Valentin, Hällberg, B. Martin, Marklund, Erik. G., Schafer, Nicholas P., Petzold, Katja, Teilum, Kaare, Wolynes, Peter G., Landreh, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197120/
https://www.ncbi.nlm.nih.gov/pubmed/37145883
http://dx.doi.org/10.1021/jacs.3c00932

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197120/
https://www.ncbi.nlm.nih.gov/pubmed/37145883
http://dx.doi.org/10.1021/jacs.3c00932

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