Cargando…

A Photoredox Reaction for the Selective Modification of 5-Carboxycytosine in DNA

[Image: see text] Covalent epigenetic modifications contribute to the regulation of important cellular processes during development and differentiation, and changes in their genomic distribution and frequency are linked to the emergence of genetic disease states. Chemical and enzymatic methods that...

Descripción completa

Detalles Bibliográficos
Autores principales: Mortishire-Smith, Benjamin J., Becker, Sidney M., Simeone, Angela, Melidis, Larry, Balasubramanian, Shankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197125/
https://www.ncbi.nlm.nih.gov/pubmed/37141595
http://dx.doi.org/10.1021/jacs.2c12558