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Expanding Transition Metal-Mediated Bioorthogonal Decaging to Include C–C Bond Cleavage Reactions

[Image: see text] The ability to control the activation of prodrugs by transition metals has been shown to have great potential for controlled drug release in cancer cells. However, the strategies developed so far promote the cleavage of C–O or C–N bonds, which limits the scope of drugs to only thos...

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Detalles Bibliográficos
Autores principales: Dal Forno, Gean M., Latocheski, Eloah, Beatriz Machado, Ana, Becher, Julie, Dunsmore, Lavinia, St. John, Albert L., Oliveira, Bruno L., Navo, Claudio D., Jiménez-Osés, Gonzalo, Fior, Rita, Domingos, Josiel B., Bernardes, Gonçalo J. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197128/
https://www.ncbi.nlm.nih.gov/pubmed/37133984
http://dx.doi.org/10.1021/jacs.3c01960