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LAPTM4B-YAP loop feedback amplification enhances the stemness of hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is highly heterogeneous, and stemness signatures are frequently elevated in HCC tumor cells to generate heterogeneous subtypes via multidirectional differentiation. However, the mechanisms affecting the regulation of stemness in HCC remain unclear. In this study, we id...

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Detalles Bibliográficos
Autores principales: Liao, Jianping, Wang, Jiahong, Xu, Yu, Wu, Yong, Wang, Meifeng, Zhao, Qiudong, Tan, Xiaodan, Meng, Yan, Wei, Lixin, Huang, Aimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197148/
https://www.ncbi.nlm.nih.gov/pubmed/37213231
http://dx.doi.org/10.1016/j.isci.2023.106754