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Rapid and accurate method for quantifying busulfan in plasma samples by isocratic liquid chromatography-tandem mass spectrometry (LC-MS/MS)

OBJECTIVES: Administration of busulfan is extending rapidly as a part of a conditioning regimen in patients undergoing hematopoietic stem cell transplantation (HSCT). Monitoring blood plasma levels of busulfan is recommended for identifying the optimal dose in patients and for minimizing toxicity. T...

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Detalles Bibliográficos
Autores principales: Villena-Ortiz, Yolanda, Castellote-Bellés, Laura, Martinez-Sanchez, Luisa, Benítez-Carabante, María I., Miarons, Marta, Vima-Bofarull, Jaume, Barquin-DelPino, Raquel, Paciucci, Rosanna, Rodríguez-Frías, Francisco, Ferrer-Costa, Roser, Casis, Ernesto, López-Hellín, Joan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197276/
https://www.ncbi.nlm.nih.gov/pubmed/37362141
http://dx.doi.org/10.1515/almed-2022-0016