Cargando…

Rapid restitution of contractile dysfunction by synthetic copolymers in dystrophin-deficient single live skeletal muscle fibers

Duchenne muscular dystrophy (DMD) is caused by the lack of dystrophin, a cytoskeletal protein essential for the preservation of the structural integrity of the muscle cell membrane. DMD patients develop severe skeletal muscle weakness, degeneration, and early death. We tested here amphiphilic synthe...

Descripción completa

Detalles Bibliográficos
Autores principales: Hahn, Dongwoo, Quick, Joseph D., Thompson, Brian R., Crabtree, Adelyn, Hackel, Benjamin J., Bates, Frank S., Metzger, Joseph M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197332/
https://www.ncbi.nlm.nih.gov/pubmed/37208786
http://dx.doi.org/10.1186/s13395-023-00318-y