Cargando…

Rapid restitution of contractile dysfunction by synthetic copolymers in dystrophin-deficient single live skeletal muscle fibers

Duchenne muscular dystrophy (DMD) is caused by the lack of dystrophin, a cytoskeletal protein essential for the preservation of the structural integrity of the muscle cell membrane. DMD patients develop severe skeletal muscle weakness, degeneration, and early death. We tested here amphiphilic synthe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hahn, Dongwoo, Quick, Joseph D., Thompson, Brian R., Crabtree, Adelyn, Hackel, Benjamin J., Bates, Frank S., Metzger, Joseph M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197332/ https://www.ncbi.nlm.nih.gov/pubmed/37208786 http://dx.doi.org/10.1186/s13395-023-00318-y

Ejemplares similares

Molecular homing and retention of muscle membrane stabilizing copolymers by non-invasive optical imaging in vivo
por: Batti Angulski, Addeli Bez, et al.
Publicado: (2022)

Consequences of poly(ethylene oxide) and poloxamer P188 on transcription in healthy and stressed myoblasts
por: Crabtree, Adelyn A., et al.
Publicado: (2023)

Sarcomere dynamics revealed by a myofilament integrated FRET-based biosensor in live skeletal muscle fibers
por: Martin, Ashley A., et al.
Publicado: (2022)

Direct visualization of the dystrophin network on skeletal muscle fiber membrane
Publicado: (1992)

Effects of Mini-Dystrophin on Dystrophin-Deficient, Human Skeletal Muscle-Derived Cells
por: Meng, Jinhong, et al.
Publicado: (2020)

Investigations of an inducible intact dystrophin gene excision system in cardiac and skeletal muscle in vivo
por: Bez Batti Angulski, Addeli, et al.
Publicado: (2020)

Membrane-stabilizing copolymers confer marked protection to dystrophic skeletal muscle in vivo
por: Houang, Evelyne M, et al.
Publicado: (2015)

Ex Vivo Stretch Reveals Altered Mechanical Properties of Isolated Dystrophin-Deficient Hearts
por: Barnabei, Matthew S., et al.
Publicado: (2012)

Confocal laser microscopy of dystrophin localization in guinea pig skeletal muscle fibers
Publicado: (1992)

Ultraslow contractile inactivation in frog skeletal muscle fibers
Publicado: (1990)

Transcriptomic analysis of dystrophin RNAi knockdown reveals a central role for dystrophin in muscle differentiation and contractile apparatus organization
por: Ghahramani Seno, Mohammad M, et al.
Publicado: (2010)

Skeletal Muscle Fiber Type: Influence on Contractile and Metabolic Properties
por: Zierath, Juleen R, et al.
Publicado: (2004)

Full-length dystrophin deficiency leads to contractile and calcium transient defects in human engineered heart tissues
por: Bremner, Samantha B, et al.
Publicado: (2022)

Effect of membrane polarization on contractile threshold and time course of prolonged contractile responses in skeletal muscle fibers
Publicado: (1984)

Dystrophin deficiency exacerbates skeletal muscle pathology in dysferlin-null mice
por: Han, Renzhi, et al.
Publicado: (2011)

Chemical crosslinking analysis of β-dystroglycan in dystrophin-deficient skeletal muscle
por: Murphy, Sandra, et al.
Publicado: (2018)

Proteomic Profiling of the Dystrophin-Deficient MDX Heart Reveals Drastically Altered Levels of Key Metabolic and Contractile Proteins
por: Lewis, Caroline, et al.
Publicado: (2010)

Climate Justice and the Duty of Restitution
por: Truccone-Borgogno, Santiago
Publicado: (2023)

The Dystrophin Node as Integrator of Cytoskeletal Organization, Lateral Force Transmission, Fiber Stability and Cellular Signaling in Skeletal Muscle
por: Dowling, Paul, et al.
Publicado: (2021)

Dystrophin and mini-dystrophin quantification by mass spectrometry in skeletal muscle for gene therapy development in Duchenne muscular dystrophy
por: Farrokhi, Vahid, et al.
Publicado: (2021)

The Proton Pump Inhibitor Lansoprazole Improves the Skeletal Phenotype in Dystrophin Deficient mdx Mice
por: Sali, Arpana, et al.
Publicado: (2013)

Ambient Experience in Restitutive Treatment of Aphasia
por: McClung, Jill S., et al.
Publicado: (2010)

Dynamic Action Potential Restitution Contributes to Mechanical Restitution in Right Ventricular Myocytes From Pulmonary Hypertensive Rats
por: Hardy, Matthew E. L., et al.
Publicado: (2018)

The subcellular distribution of dystrophin in mouse skeletal, cardiac, and smooth muscle
Publicado: (1991)

Quantitative immuno-mass spectrometry imaging of skeletal muscle dystrophin
por: Bishop, David P., et al.
Publicado: (2021)

Muscle membrane integrity in Duchenne muscular dystrophy: recent advances in copolymer-based muscle membrane stabilizers
por: Houang, Evelyne M., et al.
Publicado: (2018)

Improvement of cardiac contractile function by peptide-based inhibition of NF-κB in the utrophin/dystrophin-deficient murine model of muscular dystrophy
por: Delfín, Dawn A, et al.
Publicado: (2011)

Restitution at the cellular level: regulation of the migrating phenotype.
por: Basson, M. D., et al.
Publicado: (1996)

Molecular aspects of restitution: functions of trefoil peptides.
por: Poulsom, R., et al.
Publicado: (1996)

RESTITUTION OF PANCREATIC ACINAR CELLS FOLLOWING ETHIONINE
por: Herman, Lawrence, et al.
Publicado: (1962)

Fiber-Type Shifting in Sarcopenia of Old Age: Proteomic Profiling of the Contractile Apparatus of Skeletal Muscles
por: Dowling, Paul, et al.
Publicado: (2023)

Dystrophin-glycoprotein complex is highly enriched in isolated skeletal muscle sarcolemma
Publicado: (1991)

The biochemical and mass spectrometric profiling of the dystrophin complexome from skeletal muscle
por: Murphy, Sandra, et al.
Publicado: (2015)

Characterization of brain dystrophins absence and impact in dystrophin-deficient Dmd(mdx) rat model
por: Caudal, Dorian, et al.
Publicado: (2020)

Subcellular Localization of Dystrophin Isoforms in Cardiomyocytes and Phenotypic Analysis of Dystrophin-deficient Mice Reveal Cardiac Myopathy is Predominantly Caused by a Deficiency in Full-length Dystrophin
por: Masubuchi, Nami, et al.
Publicado: (2013)

Fetal Skeletal Muscle Progenitors Have Regenerative Capacity after Intramuscular Engraftment in Dystrophin Deficient Mice
por: Sakai, Hiroshi, et al.
Publicado: (2013)

Contractile Activation in Frog Skeletal Muscle
por: Costantin, L. L.
Publicado: (1974)

Effects of alcohol on skeletal muscle contractile performance in male and female mice
por: Laudato, Joseph A., et al.
Publicado: (2021)

GRAF1 deficiency blunts sarcolemmal injury repair and exacerbates cardiac and skeletal muscle pathology in dystrophin-deficient mice
por: Lenhart, Kaitlin C., et al.
Publicado: (2015)

Restitution of Sculptural Groups Using 3D Scanners
por: Merchán, Pilar, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_kjh7sajlfam9c5t0i6jssd1udi