Empagliflozin improves renal ischemia–reperfusion injury by reducing inflammation and enhancing mitochondrial fusion through AMPK–OPA1 pathway promotion

BACKGROUND: Renal ischemia–reperfusion injury (IRI) is one reason for renal transplantation failure. Recent studies have shown that mitochondrial dynamics is closely related to IRI, and that inhibition or reversal of mitochondrial division protects organs against IRI. Optic atrophy protein 1 (OPA1),...

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Detalles Bibliográficos
Autores principales: Yang, Wenbo, Li, Xiaoli, He, Liujie, Zhu, Shuyang, Lai, Shicong, Zhang, Xiaopeng, Huang, Zixiong, Yu, Biyue, Cui, Chunping, Wang, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197452/
https://www.ncbi.nlm.nih.gov/pubmed/37202752
http://dx.doi.org/10.1186/s11658-023-00457-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197452/
https://www.ncbi.nlm.nih.gov/pubmed/37202752
http://dx.doi.org/10.1186/s11658-023-00457-6

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