Cargando…
Interplay of macromolecular interactions during assembly of human DNA polymerase δ holoenzymes and initiation of DNA synthesis
In humans, DNA polymerase δ (Pol δ) holoenzymes, comprised of Pol δ and the processivity sliding clamp, proliferating cell nuclear antigen (PCNA), carry out DNA synthesis during lagging strand DNA replication, initiation of leading strand DNA replication, and the major DNA damage repair and toleranc...
Autores principales: | Norris, Jessica L., Rogers, Lindsey O., Pytko, Kara G., Dannenberg, Rachel L., Perreault, Samuel, Kaushik, Vikas, Kuppa, Sahiti, Antony, Edwin, Hedglin, Mark |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197535/ https://www.ncbi.nlm.nih.gov/pubmed/37215012 http://dx.doi.org/10.1101/2023.05.09.539896 |
Ejemplares similares
-
Tracking of progressing human DNA polymerase δ holoenzymes reveals distributions of DNA lesion bypass activities
por: Dannenberg, Rachel L, et al.
Publicado: (2022) -
Stepwise assembly of the human replicative polymerase holoenzyme
por: Hedglin, Mark, et al.
Publicado: (2013) -
Dynamic Assembly and Disassembly of the Human DNA Polymerase δ Holoenzyme on the Genome In Vivo
por: Drosopoulos, William C., et al.
Publicado: (2020) -
The DNA polymerase III holoenzyme contains γ and is not a trimeric polymerase
por: Dohrmann, Paul R., et al.
Publicado: (2016) -
Identification and characterization of a heterotrimeric archaeal DNA polymerase holoenzyme
por: Yan, Jiangyu, et al.
Publicado: (2017)