Cargando…

CRISPRi Gene Modulation and All-Optical Electrophysiology in Post-Differentiated Human iPSC-Cardiomyocytes

Uncovering gene-phenotype relationships can be enabled by precise gene modulation in human induced pluripotent stem-cell-derived cardiomyocytes (iPSC-CMs) and follow up phenotyping using scalable all-optical electrophysiology platforms. Such efforts towards human functional genomics can be aided by...

Descripción completa

Detalles Bibliográficos
Autores principales: Han, Julie L., Heinson, Yuli W., Chua, Christianne J., Liu, Wei, Entcheva, Emilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197536/
https://www.ncbi.nlm.nih.gov/pubmed/37214814
http://dx.doi.org/10.1101/2023.05.07.539756