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CRISPRi Gene Modulation and All-Optical Electrophysiology in Post-Differentiated Human iPSC-Cardiomyocytes
Uncovering gene-phenotype relationships can be enabled by precise gene modulation in human induced pluripotent stem-cell-derived cardiomyocytes (iPSC-CMs) and follow up phenotyping using scalable all-optical electrophysiology platforms. Such efforts towards human functional genomics can be aided by...
Autores principales: | Han, Julie L., Heinson, Yuli W., Chua, Christianne J., Liu, Wei, Entcheva, Emilia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197536/ https://www.ncbi.nlm.nih.gov/pubmed/37214814 http://dx.doi.org/10.1101/2023.05.07.539756 |
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