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Pseudorabies virus hijacks DDX3X, initiating an addictive “mad itch” and immune suppression, to facilitate viral spread

Infections with defined Herpesviruses, such as Pseudorabies virus (PRV) and Varicella zoster virus (VZV) can cause neuropathic itch, referred to as “mad itch” in multiple species. The underlying mechanisms involved in neuropathic “mad itch” are poorly understood. Here, we show that PRV infections hi...

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Detalles Bibliográficos
Autores principales: Cronin, Shane J. F., Tejada, Miguel A., Song, Ren, Laval, Kathlyn, Cikes, Domagoj, Ji, Ming, Brai, Annalaura, Stadlmann, Johannes, Novatchikova, Maria, Perlot, Thomas, Ali, Omar Hasan, Botta, Lorenzo, Decker, Thomas, Lazovic, Jelena, Hagelkruys, Astrid, Enquist, Lynn, Rao, Shuan, Koyuncu, Orkide O., Penninger, Josef M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197578/
https://www.ncbi.nlm.nih.gov/pubmed/37214906
http://dx.doi.org/10.1101/2023.05.09.539956