Cargando…
Pseudorabies virus hijacks DDX3X, initiating an addictive “mad itch” and immune suppression, to facilitate viral spread
Infections with defined Herpesviruses, such as Pseudorabies virus (PRV) and Varicella zoster virus (VZV) can cause neuropathic itch, referred to as “mad itch” in multiple species. The underlying mechanisms involved in neuropathic “mad itch” are poorly understood. Here, we show that PRV infections hi...
Autores principales: | Cronin, Shane J. F., Tejada, Miguel A., Song, Ren, Laval, Kathlyn, Cikes, Domagoj, Ji, Ming, Brai, Annalaura, Stadlmann, Johannes, Novatchikova, Maria, Perlot, Thomas, Ali, Omar Hasan, Botta, Lorenzo, Decker, Thomas, Lazovic, Jelena, Hagelkruys, Astrid, Enquist, Lynn, Rao, Shuan, Koyuncu, Orkide O., Penninger, Josef M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197578/ https://www.ncbi.nlm.nih.gov/pubmed/37214906 http://dx.doi.org/10.1101/2023.05.09.539956 |
Ejemplares similares
-
The Neuropathic Itch Caused by Pseudorabies Virus
por: Laval, Kathlyn, et al.
Publicado: (2020) -
CRISPR/Cas9-Constructed Pseudorabies Virus Mutants Reveal the Importance of UL13 in Alphaherpesvirus Escape from Genome Silencing
por: Van Cleemput, Jolien, et al.
Publicado: (2021) -
A Pseudorabies Virus Serine/Threonine Kinase, US3, Promotes Retrograde Transport in Axons via Akt/mToRC1
por: Esteves, Andrew D., et al.
Publicado: (2022) -
The Potential Role of Herpes Simplex Virus Type 1 and Neuroinflammation in the Pathogenesis of Alzheimer's Disease
por: Laval, Kathlyn, et al.
Publicado: (2021) -
AN EXPERIMENTAL STUDY OF "MAD ITCH" WITH ESPECIAL REFERENCE TO ITS RELATIONSHIP TO PSEUDORABIES
por: Shope, Richard E.
Publicado: (1931)