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Optogenetic inhibition of Gα signalling alters and regulates circuit functionality and early circuit formation

Optogenetic techniques provide genetically targeted, spatially and temporally precise approaches to correlate cellular activities and physiological outcomes. In the nervous system, G-protein-coupled receptors (GPCRs) have essential neuromodulatory functions through binding extracellular ligands to i...

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Detalles Bibliográficos
Autores principales: Lockyer, Jayde, Reading, Andrew, Vicenzi, Silvia, Delandre, Caroline, Marshall, Owen, Gasperini, Robert, Foa, Lisa, Lin, John Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197587/
https://www.ncbi.nlm.nih.gov/pubmed/37214843
http://dx.doi.org/10.1101/2023.05.06.539674