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Stability of dentate gyrus granule cell mossy fiber BDNF protein expression with age and resistance of granule cells to Alzheimer’s disease neuropathology in a mouse model

The neurotrophin brain-derived neurotrophic factor (BDNF) is important in development and maintenance of neurons and their plasticity. Hippocampal BDNF has been implicated Alzheimer’s disease (AD) because hippocampal levels in AD patients and AD animal models are consistently downregulated, suggesti...

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Detalles Bibliográficos
Autores principales: Criscuolo, Chiara, Chartampila, Elissavet, Ginsberg, Stephen D., Scharfman, Helen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197599/
https://www.ncbi.nlm.nih.gov/pubmed/37214931
http://dx.doi.org/10.1101/2023.05.07.539742