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Dark nanodiscs as a model membrane for evaluating membrane protein thermostability by differential scanning fluorimetry

Measuring protein thermostability provides valuable information on the biophysical rules that govern structure-energy relationships of proteins. However, such measurements remain a challenge for membrane proteins. Here, we introduce a new experimental system to evaluate membrane protein thermostabil...

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Detalles Bibliográficos
Autores principales: Selvasingh, Jazlyn A., McDonald, Eli Fritz, Mckinney, Jacob R., Meiler, Jens, Ledwitch, Kaitlyn V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197605/
https://www.ncbi.nlm.nih.gov/pubmed/37214798
http://dx.doi.org/10.1101/2023.05.08.539917