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Dark nanodiscs as a model membrane for evaluating membrane protein thermostability by differential scanning fluorimetry
Measuring protein thermostability provides valuable information on the biophysical rules that govern structure-energy relationships of proteins. However, such measurements remain a challenge for membrane proteins. Here, we introduce a new experimental system to evaluate membrane protein thermostabil...
Autores principales: | Selvasingh, Jazlyn A., McDonald, Eli Fritz, Mckinney, Jacob R., Meiler, Jens, Ledwitch, Kaitlyn V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197605/ https://www.ncbi.nlm.nih.gov/pubmed/37214798 http://dx.doi.org/10.1101/2023.05.08.539917 |
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