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Dissociating instructive from permissive roles of brain circuits with reversible neural activity manipulations

Neuroscientists rely on targeted perturbations and lesions to causally map functions in the brain(1). Yet, since the brain is highly interconnected, manipulation of one area can impact behavior through indirect effects on many other brain regions, complicating the interpretation of such results(2,3)...

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Detalles Bibliográficos
Autores principales: Quintana, Daniel, Bounds, Hayley A., Brown, Jennifer, Wang, May, Bhatla, Nikhil, Wiegert, J. Simon, Adesnik, Hillel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197619/
https://www.ncbi.nlm.nih.gov/pubmed/37214966
http://dx.doi.org/10.1101/2023.05.11.540397