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Transcription-Coupled Repair of DNA Interstrand Crosslinks by UVSSA

DNA interstrand crosslinks (ICLs) are covalent bonds between opposing strands of the DNA helix which prevent DNA melting and subsequent DNA replication or RNA transcription. Here, we show that UV Stimulated Scaffold Protein A (UVSSA) participates in transcription-coupled repair of ICLs. UVSSA encode...

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Detalles Bibliográficos
Autores principales: Liebau, Rowyn Church, Waters, Crystal, Ahmed, Arooba, Soni, Rajesh K, Gautier, Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197625/
https://www.ncbi.nlm.nih.gov/pubmed/37214867
http://dx.doi.org/10.1101/2023.05.10.538304