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Orientia tsutsugamushi: analysis of the mobilome of a highly fragmented and repetitive genome reveals ongoing lateral gene transfer in an obligate intracellular bacterium

The rickettsial human pathogen Orientia tsutsugamushi (Ot) is an obligate intracellular Gram-negative bacterium with one of the most highly fragmented and repetitive genomes of any organism. Around 50% of its ~2.3 Mb genome is comprised of repetitive DNA that is derived from the highly proliferated...

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Detalles Bibliográficos
Autores principales: Giengkam, Suparat, Kullapanich, Chitrasak, Wongsantichon, Jantana, Adcox, Haley E., Gillespie, Joseph J., Salje, Jeanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197636/
https://www.ncbi.nlm.nih.gov/pubmed/37215039
http://dx.doi.org/10.1101/2023.05.11.540415