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Metabolic response of microglia to amyloid deposition during Alzheimer’s disease progression in a mouse model

Alzheimer’s disease (AD) drives metabolic changes in the central nervous system (CNS). In AD microglia are activated and proliferate in response to amyloid β plaques. To further characterize the metabolic changes in microglia associated with plaque deposition in situ, we examined cortical tissue fro...

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Detalles Bibliográficos
Autores principales: Marino, Kaitlyn M., Squirrell, Jayne M., Chacko, Jenu V., Watters, Jyoti W., Eliceiri, Kevin W., Ulland, Tyler K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197659/
https://www.ncbi.nlm.nih.gov/pubmed/37214940
http://dx.doi.org/10.1101/2023.05.12.540407