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Dysregulation of amino acid metabolism upon rapid depletion of cap-binding protein eIF4E

Protein synthesis is a crucial but metabolically costly biological process that must be tightly coordinated with cellular needs and nutrient availability. In response to environmental stress, translation initiation is modulated to control protein output while meeting new demands. The cap-binding pro...

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Detalles Bibliográficos
Autores principales: Diamond, Paige D., McGlincy, Nicholas J., Ingolia, Nicholas T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197679/
https://www.ncbi.nlm.nih.gov/pubmed/37214807
http://dx.doi.org/10.1101/2023.05.11.540079