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Differentiation-dependent chromosomal organization changes in normal myogenic cells are absent in rhabdomyosarcoma cells

Myogenesis, the progression of proliferating skeletal myoblasts to terminally differentiated myotubes, regulates thousands of target genes. Uninterrupted linear arrays of such genes are differentially associated with specific chromosomes, suggesting chromosome specific regulatory roles in myogenesis...

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Detalles Bibliográficos
Autores principales: Ibarra, Joe, Hershenhouse, Tyler, Almassalha, Luay, MacQuarrie, Kyle L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197681/
https://www.ncbi.nlm.nih.gov/pubmed/37214969
http://dx.doi.org/10.1101/2023.05.11.540394