Enhlink infers distal and context-specific enhancer-promoter linkages

Enhancers play a crucial role in regulating gene expression and their functional status can be queried with cell type precision using using single-cell (sc)ATAC-seq. To facilitate analysis of such data, we developed Enhlink, a novel computational approach that leverages single-cell signals to infer...

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Detalles Bibliográficos
Autores principales: Poirion, Olivier B., Zuo, Wulin, Spruce, Catrina, Daigle, Sandra L., Olson, Ashley, Skelly, Daniel A., Chesler, Elissa J., Baker, Christopher L., White, Brian S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197707/
https://www.ncbi.nlm.nih.gov/pubmed/37214950
http://dx.doi.org/10.1101/2023.05.11.540453

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197707/
https://www.ncbi.nlm.nih.gov/pubmed/37214950
http://dx.doi.org/10.1101/2023.05.11.540453

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