A developmental gradient reveals biosynthetic pathways to eukaryotic toxins in monocot geophytes

Numerous eukaryotic toxins that accumulate in geophytic plants are valuable in the clinic, yet their biosynthetic pathways have remained elusive. A lead example is the >150 Amaryllidaceae alkaloids (AmAs) including galantamine, an FDA-approved treatment for Alzheimer’s disease. We show that while...

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Detalles Bibliográficos
Autores principales: Mehta, Niraj, Meng, Yifan, Zare, Richard, Kamenetsky-Goldstein, Rina, Sattely, Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197729/
https://www.ncbi.nlm.nih.gov/pubmed/37214939
http://dx.doi.org/10.1101/2023.05.12.540595

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197729/
https://www.ncbi.nlm.nih.gov/pubmed/37214939
http://dx.doi.org/10.1101/2023.05.12.540595

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