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A developmental gradient reveals biosynthetic pathways to eukaryotic toxins in monocot geophytes
Numerous eukaryotic toxins that accumulate in geophytic plants are valuable in the clinic, yet their biosynthetic pathways have remained elusive. A lead example is the >150 Amaryllidaceae alkaloids (AmAs) including galantamine, an FDA-approved treatment for Alzheimer’s disease. We show that while...
Autores principales: | Mehta, Niraj, Meng, Yifan, Zare, Richard, Kamenetsky-Goldstein, Rina, Sattely, Elizabeth |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197729/ https://www.ncbi.nlm.nih.gov/pubmed/37214939 http://dx.doi.org/10.1101/2023.05.12.540595 |
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