Pyruvate dehydrogenase complex integrates the metabolome and epigenome in CD8+ memory T cell differentiation in vitro

Modulation of metabolic flux through pyruvate dehydrogenase complex (PDC) plays an important role in T cell activation and differentiation. PDC sits at the transition between glycolysis and the tricarboxylic acid cycle and is a major producer of acetyl-CoA, marking it as a potential metabolic and ep...

Descripción completa

Detalles Bibliográficos
Autores principales: Tarasenko, Tatiana, Banerjee, Payal, Gomez-Rodriguez, Julio, Gildea, Derek, Zhang, Suiyuan, Wolfsberg, Tyra, Jenkins, Lisa, McGuire, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197744/
https://www.ncbi.nlm.nih.gov/pubmed/37215014
http://dx.doi.org/10.21203/rs.3.rs-2838359/v1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197744/
https://www.ncbi.nlm.nih.gov/pubmed/37215014
http://dx.doi.org/10.21203/rs.3.rs-2838359/v1

Ejemplares similares