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Pyruvate dehydrogenase complex integrates the metabolome and epigenome in CD8+ memory T cell differentiation in vitro

Modulation of metabolic flux through pyruvate dehydrogenase complex (PDC) plays an important role in T cell activation and differentiation. PDC sits at the transition between glycolysis and the tricarboxylic acid cycle and is a major producer of acetyl-CoA, marking it as a potential metabolic and ep...

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Detalles Bibliográficos
Autores principales:	Tarasenko, Tatiana, Banerjee, Payal, Gomez-Rodriguez, Julio, Gildea, Derek, Zhang, Suiyuan, Wolfsberg, Tyra, Jenkins, Lisa, McGuire, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Journal Experts 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197744/ https://www.ncbi.nlm.nih.gov/pubmed/37215014 http://dx.doi.org/10.21203/rs.3.rs-2838359/v1

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