Distinct genetic liability profiles define clinically relevant patient strata across common diseases

Genome-wide association studies have unearthed a wealth of genetic associations across many complex diseases. However, translating these associations into biological mechanisms contributing to disease etiology and heterogeneity has been challenging. Here, we hypothesize that the effects of disease-a...

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Detalles Bibliográficos
Autores principales: Trastulla, Lucia, Moser, Sylvain, Jiménez-Barrón, Laura T., Andlauer, Till F.M., von Scheidt, Moritz, Budde, Monika, Heilbronner, Urs, Papiol, Sergi, Teumer, Alexander, Homuth, Georg, Falkai, Peter, Völzke, Henry, Dörr, Marcus, Schulze, Thomas G., Gagneur, Julien, Iorio, Francesco, Müller-Myhsok, Bertram, Schunkert, Heribert, Ziller, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197798/
https://www.ncbi.nlm.nih.gov/pubmed/37214898
http://dx.doi.org/10.1101/2023.05.10.23289788

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197798/
https://www.ncbi.nlm.nih.gov/pubmed/37214898
http://dx.doi.org/10.1101/2023.05.10.23289788

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