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Targeting the inward rectifier potassium channel 5.1 in thyroid cancer: artificial intelligence-facilitated molecular docking for drug discovery

BACKGROUND: Recurrent and metastatic thyroid cancer is more invasive and can transform to dedifferentiated thyroid cancer, thus leading to a severe decline in the 10-year survival. The thyroid-stimulating hormone receptor (TSHR) plays an important role in differentiation process. We aim to find a th...

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Detalles Bibliográficos
Autores principales: Yang, Xue, Wu, Yonglin, Xu, Shaojie, Li, Hanning, Peng, Chengcheng, Cui, Xiaoqing, Dhoomun, Deenraj Kush, Wang, Ge, Xu, Tao, Dong, Menglu, Li, Xingrui, Du, Yaying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197823/
https://www.ncbi.nlm.nih.gov/pubmed/37208644
http://dx.doi.org/10.1186/s12902-023-01360-z