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Yields and product comparison between Escherichia coli BL21 and W3110 in industrially relevant conditions: anti-c-Met scFv as a case study

INTRODUCTION: In the biopharmaceutical industry, Escherichia coli is one of the preferred expression hosts for large-scale production of therapeutic proteins. Although increasing the product yield is important, product quality is a major factor in this industry because greatest productivity does not...

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Detalles Bibliográficos
Autores principales: Arauzo-Aguilera, Klaudia, Buscajoni, Luisa, Koch, Karin, Thompson, Gary, Robinson, Colin, Berkemeyer, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197847/
https://www.ncbi.nlm.nih.gov/pubmed/37208750
http://dx.doi.org/10.1186/s12934-023-02111-4