PU.1-driven Th9 Cells Promote Colorectal Cancer in Experimental Colitis Models Through Il-6 Effects in Intestinal Epithelial Cells

BACKGROUND AND AIMS: Colorectal cancer [CRC] is one of the most frequent malignancies, but the molecular mechanisms driving cancer growth are incompletely understood. We characterised the roles of the cytokine IL-9 and Th9 cells in regulating CRC development. METHODS: CRC patient samples and samples...

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Detalles Bibliográficos
Autores principales: Gerlach, Katharina, Popp, Vanessa, Wirtz, Stefan, Al-Saifi, Ragheed, Gonzalez Acera, Miguel, Atreya, Raja, Dregelies, Theresa, Vieth, Michael, Fichtner-Feigl, Stefan, McKenzie, Andrew N J, Rosenbauer, Frank, Weigmann, Benno, Neurath, Markus F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197880/
https://www.ncbi.nlm.nih.gov/pubmed/35793807
http://dx.doi.org/10.1093/ecco-jcc/jjac097

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197880/
https://www.ncbi.nlm.nih.gov/pubmed/35793807
http://dx.doi.org/10.1093/ecco-jcc/jjac097

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