Venetoclax Penetrates the Blood Brain Barrier: A Pharmacokinetic Analysis in Pediatric Leukemia Patients

Infiltration of malignant cells into the central nervous system in hematological malignancies correlates with poor clinical outcomes. Investigations into the penetration of venetoclax into the central nervous system have been limited. We report venetoclax pharmacokinetics in plasma and cerebrospinal...

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Detalles Bibliográficos
Autores principales: Badawi, Mohamed, Menon, Rajeev, Place, Andrew E., Palenski, Tammy, Sunkersett, Gauri, Arrendale, Richard, Deng, Rong, Federico, Sara M., Cooper, Todd M., Salem, Ahmed Hamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197937/
https://www.ncbi.nlm.nih.gov/pubmed/37215448
http://dx.doi.org/10.7150/jca.81795

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197937/
https://www.ncbi.nlm.nih.gov/pubmed/37215448
http://dx.doi.org/10.7150/jca.81795

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