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Acetylation of PPARγ in macrophages promotes visceral fat degeneration in obesity

Obesity is characterized by chronic, low-grade inflammation, which is driven by macrophage infiltration of adipose tissue. PPARγ is well established to have an anti-inflammatory function in macrophages, but the mechanism that regulates its function in these cells remains to be fully elucidated. PPAR...

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Detalles Bibliográficos
Autores principales: Aaron, Nicole, Zahr, Tarik, He, Ying, Yu, Lexiang, Mayfield, Brent, Pajvani, Utpal B., Qiang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10198133/
https://www.ncbi.nlm.nih.gov/pubmed/37213714
http://dx.doi.org/10.1093/lifemeta/loac032