Alcohol and Ganaxolone Suppress Tremor via Extra-Synaptic GABA(A) Receptors in the Harmaline Model of Essential Tremor

BACKGROUND: A long-standing question is why essential tremor often responds to non-intoxicating amounts of alcohol. Blood flow imaging and high-density electroencephalography have indicated that alcohol acts on tremor within the cerebellum. As extra-synaptic δ-subunit-containing GABA(A) receptors ar...

Descripción completa

Detalles Bibliográficos
Autores principales: Handforth, Adrian, Kosoyan, Hovsep P., Kadam, Pournima A., Singh, Ram P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ubiquity Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10198231/
https://www.ncbi.nlm.nih.gov/pubmed/37214542
http://dx.doi.org/10.5334/tohm.760

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10198231/
https://www.ncbi.nlm.nih.gov/pubmed/37214542
http://dx.doi.org/10.5334/tohm.760

Ejemplares similares