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Alcohol and Ganaxolone Suppress Tremor via Extra-Synaptic GABA(A) Receptors in the Harmaline Model of Essential Tremor

BACKGROUND: A long-standing question is why essential tremor often responds to non-intoxicating amounts of alcohol. Blood flow imaging and high-density electroencephalography have indicated that alcohol acts on tremor within the cerebellum. As extra-synaptic δ-subunit-containing GABA(A) receptors ar...

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Detalles Bibliográficos
Autores principales:	Handforth, Adrian, Kosoyan, Hovsep P., Kadam, Pournima A., Singh, Ram P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ubiquity Press 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10198231/ https://www.ncbi.nlm.nih.gov/pubmed/37214542 http://dx.doi.org/10.5334/tohm.760

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