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Mice lacking Ptprd exhibit deficits in goal-directed behavior and female-specific impairments in sensorimotor gating

Protein Tyrosine Phosphatase receptor type D (PTPRD) is a member of the protein tyrosine phosphatase family that mediates cell adhesion and synaptic specification. Genetic studies have linked Ptprd to several neuropsychiatric phenotypes, including Restless Leg Syndrome (RLS), opioid abuse disorder,...

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Detalles Bibliográficos
Autores principales: Ho, Emily V., Welch, Amanda, Thompson, Summer L., Knowles, James A., Dulawa, Stephanie C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10198499/
https://www.ncbi.nlm.nih.gov/pubmed/37205689
http://dx.doi.org/10.1371/journal.pone.0277446