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Sporothrix globosa melanin regulates autophagy via the TLR2 signaling pathway in THP-1 macrophages

Melanin, an important virulence factor of pathogenic fungi, has been shown to suppress host immune responses in multiple ways. Autophagy is a vital cellular mechanism underlying the host’s innate immunity against microbial infections. However, the potential influence of melanin on autophagy has not...

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Detalles Bibliográficos
Autores principales: Guan, Mengqi, Yao, Lei, Zhen, Yu, Song, Yang, Liu, Xiaobo, Liu, Yuanyuan, Chen, Ruili, Cui, Yan, Li, Shanshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10198546/
https://www.ncbi.nlm.nih.gov/pubmed/37141335
http://dx.doi.org/10.1371/journal.pntd.0011281