PCNA Ser46-Leu47 residues are crucial in preserving genomic integrity

Proliferating cell nuclear antigen (PCNA) is a maestro of DNA replication. PCNA forms a homotrimer and interacts with various proteins, such as DNA polymerases, DNA ligase I (LIG1), and flap endonuclease 1 (FEN1) for faithful DNA replication. Here, we identify the crucial role of Ser46-Leu47 residue...

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Detalles Bibliográficos
Autores principales: Kim, Sangin, Kim, Yeongjae, Kim, Youyoung, Yoon, Suhyeon, Lee, Kyoo-young, Lee, Yoonsung, Kang, Sukhyun, Myung, Kyungjae, Oh, Chang-Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10198555/
https://www.ncbi.nlm.nih.gov/pubmed/37205694
http://dx.doi.org/10.1371/journal.pone.0285337

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10198555/
https://www.ncbi.nlm.nih.gov/pubmed/37205694
http://dx.doi.org/10.1371/journal.pone.0285337

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