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ConFERMing the role of talin in integrin activation and mechanosignaling

Talin (herein referring to the talin-1 form), is a cytoskeletal adapter protein that binds integrin receptors and F-actin, and is a key factor in the formation and regulation of integrin-dependent cell–matrix adhesions. Talin forms the mechanical link between the cytoplasmic domain of integrins and...

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Detalles Bibliográficos
Autores principales: Bachmann, Michael, Su, Baihao, Rahikainen, Rolle, Hytönen, Vesa P., Wu, Jinhua, Wehrle-Haller, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10198623/
https://www.ncbi.nlm.nih.gov/pubmed/37078342
http://dx.doi.org/10.1242/jcs.260576