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ConFERMing the role of talin in integrin activation and mechanosignaling
Talin (herein referring to the talin-1 form), is a cytoskeletal adapter protein that binds integrin receptors and F-actin, and is a key factor in the formation and regulation of integrin-dependent cell–matrix adhesions. Talin forms the mechanical link between the cytoplasmic domain of integrins and...
Autores principales: | Bachmann, Michael, Su, Baihao, Rahikainen, Rolle, Hytönen, Vesa P., Wu, Jinhua, Wehrle-Haller, Bernhard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10198623/ https://www.ncbi.nlm.nih.gov/pubmed/37078342 http://dx.doi.org/10.1242/jcs.260576 |
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