Deletion of p75(NTR) rescues the synaptic but not the inflammatory status in the brain of a mouse model for Alzheimer’s disease

INTRODUCTION: Alzheimer’s disease (AD), is characterized by a gradual cognitive decline associated with the accumulation of Amyloid beta (Aβ)-oligomers, progressive neuronal degeneration and chronic neuroinflammation. Among the receptors shown to bind and possibly transduce the toxic effects of Aβ-o...

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Detalles Bibliográficos
Autores principales: Demuth, Hendrik, Hosseini, Shirin, Düsedeau, Henning Peter, Dunay, Ildiko Rita, Korte, Martin, Zagrebelsky, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Molecular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10198655/
https://www.ncbi.nlm.nih.gov/pubmed/37213691
http://dx.doi.org/10.3389/fnmol.2023.1163087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10198655/
https://www.ncbi.nlm.nih.gov/pubmed/37213691
http://dx.doi.org/10.3389/fnmol.2023.1163087

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